About the Treatment
Rejuvenate and repair your skin with polynucleotides
Polynucleotides are cutting-edge injectable treatments that repair, hydrate, and rejuvenate the skin at a cellular level. By stimulating collagen production and enhancing skin regeneration, they improve elasticity, texture, and hydration while reducing fine lines and inflammation. Ideal for ageing, dull, or compromised skin, polynucleotides promote natural skin renewal for a fresher, healthier complexion.
At Smooth Dimensions, our Advanced Aesthetic Nurse, Fiona Mahandru, is highly skilled in administering Polynucleotide treatments. Using a personalised approach, Fiona ensures subtle, natural results that enhance your skin’s health and appearance.
Conditions & concerns that can be treated
About the Treatment
At a glance
Appointment duration
30 minutes
Downtime
24 hours
Results visible
2 – 3 weeks – full results developing over time
Longevity
6 – 9 months
Key benefits
Boosts collagen & elastin
Deeply hydrates & plumps the skin
Improves skin texture & elasticity
Reduces fine lines & wrinkles
Calms inflammation & supports healing

Why Smooth Dimensions
Leading medical aesthetics clinic in Dunmow, Essex
Using our extensive variety of treatment options, and drawing upon the most advanced medical expertise, our goal is to provide all our clients with exceptional care and the best possible outcomes. All of our procedures are carried out by our founder and Advanced Aesthetic Nurse Prescriber, Fiona Mahandru. Find out more.

Fiona Mahandru
Advanced Nurse Prescriber
Treatment Pricing
Price list
1st treatment
£250
2nd treatment
£250
3rd treatment
£200
Payment plans available
Treatment FAQs
Frequently asked questions
Are there side effects?
Mild side effects such as redness, swelling, or bruising at the injection sites are common but typically resolve within a few days.
Can polynucleotides be combined with other treatments?
Yes, polynucleotides can be combined with treatments such as Botox®, dermal fillers or skin boosters for enhanced skin rejuvenation.
Does the treatment hurt?
Most patients experience minimal discomfort. Numbing cream can be applied before the procedure to ensure comfort.
How do polynucleotides work?
Polynucleotides stimulate skin repair at the cellular level, boost hydration, and improve elasticity and firmness.
How long do the results last?
Results typically last around 6 to 9 months, depending on individual factors such as skin condition and lifestyle. Maintenance treatments are recommended to continue to see improvements.
How long does the procedure take?
The treatment typically takes 30 – 45 minutes.
How many treatments are needed?
A minimum of 3 treatments, spaced 2 – 3 weeks apart, is recommended for optimal results. Followed by maintenance treatments every 6 – 9 months.
How much does the treatment cost?
Pricing at Smooth Dimensions varies depending on the treatment plan. A consultation will provide a personalised quote. A guidance for pricing can be found above.
Is the treatment safe?
Yes, polynucleotides are safe when administered by a qualified professional such as our Advanced Aesthetic Nurse, Fiona Mahandru. Fiona has extensive experience and training in administering polynucleotides. Find out more about her qualifications and accreditations here.
Is there any downtime?
There is little to no downtime. Most patients resume normal activities immediately, though strenuous exercise should be avoided for 24 hours. Slight redness, swelling, and small bumps are often present at the injection sites, usually resolving within a few hours to 24 hours. May be some mild bruising. To minimise downtime, avoid alcohol, strenuous exercise, heat exposure (saunas, steam rooms), and makeup for 24 hours.
What are polynucleotides?
Polynucleotides are biostimulatory molecules that repair and rejuvenate the skin by improving collagen production, hydration, and cell regeneration.
When will I see results?
Initial improvements can be seen after 2 – 3 weeks, with continued enhancements as the skin regenerates and once the initial course has been completed. It's important to maintain with treatments every 6 to 9 months to continue seeing improvements.
Which areas can Polynucleotides treat?
Polynucleotides can be used to treat many areas by stimulating collagen production and enhancing skin regeneration. Treatment areas include:
- Face, including under-eyes
- Neck & décolletage
- Hands
- Scalp – for hair restoration
- Areas with scarring or skin damage – e.g. rosacea, pigmentation
Any other questions?
Book a polynucleotides appointment
Book an appointment at our clinic in Great Dunmow, Essex. If you’re not sure what treatment you would like, book a consultation or message us with your questions.